Encouraging results with epilepsy -Dogs The veterinary team behind the ongoing clinical trial has found that 89% of dogs who received cannabidiol had a reduction in frequency of seizures. References: Mechoulam R, Parker LA. The endocannabinoid system and the brain. Anne Rev Psychol. 2013;64:21-47. Jones NA, Hill AJ, Bevan SA, et al. Cannabidiol displays antiepileptiform and antiseziure properties in vitro and in vivo. J Pharmacy Exp there. 2010 Feb;332(2):569-77. Devinsky O, Marsh E, Friedman D et al. Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. Lancet Neurol. 2016 Mar;15(3):270-278. Sulak D, Santo R, Goldstein B. The current status of artisinal cannabis for the treatment of epilepsy in the United States. Epilepsy Behav, May 2017, 70(Pt B), 328-333. Perucca E. Cannabinoids in the treatment of epilepsy: hard evidence at last? J Epilepsy Res. 2017 Dec; 7(2): 61-76. Klots KA, Grob D, Hirsch M, et al. Efficacy and tolerance of synthetic cannabidiol for treatment of drug resistant epilepsy. Front Neurol. 2019; 10: 1313. Gaston TE, Friedman D. Pharmacology of cannabinoids in the treatment of epilepsy. Epilepsy & Behavior 70 (2017):313-318.
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